October 23, 2024 — NCI has launched myeloMATCH, a precision medicine treatment trial for people with acute myeloid leukemia and myelodysplastic syndromes.
August 8, 2024 — Adding a JAK inhibitor to an immune checkpoint inhibitor shrank tumors in more than half of trial participants with lung cancer or lymphoma.
July 9, 2024 — A large clinical trial looks to have settled a debate over how best to treat most people with locally advanced esophageal cancer, where the disease has spread just outside of the esophagus but not to other parts of the body.
June 11, 2024 — A nanoparticle-based mRNA vaccine improved survival in dogs with brain cancer and induced rapid immune responses in a small study in humans with glioblastoma.
May 21, 2024 — Pembrolizumab (Keytruda) treatment after surgery helped people with clear-cell renal cell carcinoma live longer in a large trial—a first for this cancer.
August 24, 2023 — The OPTIMUM study aims to improve the care of people with low-grade glioma by learning more about the biology of the disease and engaging participants in research.
June 27, 2023 — The investigational drug vorasidenib substantially slowed the growth of tumors in people with low-grade gliomas that had mutations in the IDH1 or IDH2 genes.
June 1, 2023 — ComboMATCH will comprise numerous phase 2 precision medicine cancer treatment trials that aim to identify promising drug combinations that can advance to larger clinical trials.
May 25, 2023 — NIH-funded research effort identifies most common symptoms, potential subgroups, and initial symptom-based scoring system – with aim of improving future diagnostics and treatment.
April 11, 2023 — For older adults whose depression persisted while taking an antidepressant, adding aripiprazole had greater benefits than switching to another antidepressant.
January 19, 2023 — When breast cancer metastasizes to the brain, new tumors usually develop even after treatment. But recurrence was low among women who received low-dose temozolomide with T-DM1 in a phase I clinical trial.
January 11, 2023 — The initial treatment used for some younger women with an aggressive form of breast cancer may be about to change, based on results of a new clinical trial.
December 28, 2022 — A clinical trial led by NCI has resulted in FDA approval of the immunotherapy drug atezolizumab (Tecentriq) to treat advanced alveolar soft part sarcoma.
October 12, 2022 — For some people with melanoma, pembrolizumab (Keytruda) before surgery may be better than getting the immunotherapy only after surgery, a new study shows.
October 4, 2022 — The trial is evaluating whether the bacteriophage therapy is safe and able to reduce the amount of bacteria in the lungs of volunteers.
April 21, 2022 — NIH-funded study finds many patients with retinal vein occlusion have vision benefits, but require long-term monitoring and treatment.
September 15, 2021 — NIH launched the RECOVER Initiative to learn why some people have prolonged symptoms or develop new or returning symptoms after the acute phase of infection from SARS-CoV-2.
December 29, 2020 — Adults who have been diagnosed with metastatic breast cancer may be eligible to participate in a clinical trial at the NIH Clinical Center.
Thursday, September 10, 2020 — The trials will be conducted at more than 100 sites around the world and will involve patients in various clinical settings.
Wednesday, July 15, 2020 — While treatment options for many forms of cancer have advanced rapidly over recent decades, therapies for some rare and aggressive forms of cancer remain limited.
Wednesday, April 29, 2020 — Preliminary results indicate that patients who received remdesivir had a 31% faster time to recovery than those who received placebo.
Tuesday, December 10, 2019 — Blinatumomab is superior to standard chemotherapy for children and young adults with high- or intermediate-risk B-cell acute lymphoblastic leukemia that has relapsed.
October 23, 2019 — A clinical trial in which healthy adults will be deliberately infected with influenza virus under carefully controlled conditions is recruiting volunteers at four Vaccine and Treatment Evaluation Units (VTEUs) supported by the National Institute of Allergy and Infectious Diseases (NIAID).
September 20, 2019 — Feinstein Institutes for Medical Research scientists have been awarded a five-year, $7.3 million National Institutes of Mental Health (NIMH) grant to support their research in improved schizophrenia treatment.
September 5, 2019 — Follicular lymphoma (FL) is a cancer of white blood cells (B cells) that help your body fight infections. Investigators are leading a clinical trial at the NIH Clinical Center to see if a combination therapy can slow the growth of FL in patients who have not received prior treatment.
August 26, 2019 — James N. Kochenderfer, M.D., Investigator in the Surgery Branch, is leading a study of a new way to treat multiple myeloma (MM) that uses a patient’s own T cells to target MM cells. MM is a rare blood cancer that occurs in blood, tissues, bone and bone marrow. With MM, a group of plasma cells become cancerous and multiply, crowding out healthy blood cells.
July 10, 2019 — Dogs are, no doubt, man’s best friend. So, it’s no surprise that people will do almost anything for their dogs. But what can a person do if their dog is given a devastating diagnosis of cancer?
June 14, 2019 — National Institutes of Health scientists have used human skin cells to create what they believe is the first cerebral organoid system, or “mini-brain,” for studying sporadic Creutzfeldt-Jakob disease (CJD).
March 28, 2019 — A new study provides insight into how cancer immunotherapy works and suggests ways to enhance the treatment’s effectiveness. The NCI-led study, published in Science, examined the effect of high potassium levels on T cells.
February 26, 2019 — James and Jahleel are a father-daughter duo from Tennessee who came to NIH for Jahleel’s bone marrow transplant. Jahleel was diagnosed with GATA2 deficiency, a rare genetic disease that causes a wide range of symptoms, including myeloid leukemias.
February 11, 2019 — Natural News reported a study led by Dr. Steven Moore of the National Cancer Institute found “regular exercise – in particular, aerobic exercise – can lower your risk of about 13 different types of cancer.”
February 1, 2019 — The Lung Cancer Master Protocol (Lung-MAP), the first precision medicine trial in lung cancer supported by the National Cancer Institute (NCI), is undergoing a major expansion to include patients with all non–small cell lung cancers (NSCLCs).
January 30, 2019 — Scientists funded by the National Institutes of Health have developed a new assay to accurately and easily count the cells that comprise the HIV reservoir, the stubborn obstacle to an HIV cure.
January 14, 2019 — Clostridium difficile, commonly referred to as C. diff, is a bacterium that infects the colon and can cause diarrhea, fever, and abdominal pain.
August 16, 2018 — Vaccinations have begun in a first-in-human trial of an experimental live, attenuated Zika virus vaccine developed by scientists at the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health.
July 10, 2018 — Veterans with cancer who receive treatment from the Department of Veterans Affairs (VA) will now have easier access to clinical trials of novel cancer treatments, thanks to an agreement between VA and the National Cancer Institute (NCI), part of the National Institutes of Health.
June 4, 2018 — A novel approach to immunotherapy developed by researchers at the National Cancer Institute (NCI) has led to the complete regression of breast cancer in a patient who was unresponsive to all other treatments.
January 3, 2018 — It’s not often that a cancer clinical trial recruits a handful of oncologists to staff a round-the-clock help desk of sorts for their peers. But that’s the case for a unique NCI-funded trial that is attempting to address a serious problem for patients who have a very rare cancer, acute promyelocytic leukemia (APL).
November 28, 2017 — A recent NIAAA study has shown that people who drink socially and have certain risk factors for alcohol use disorder (AUD) self-administer more alcohol and at a faster rate during a single session of alcohol consumption in a laboratory setting than people at low risk for developing AUD.
October 17, 2017 — Two test vaccines for Ebola were safe and induced lasting immune responses in a study with 1,500 adults in Liberia. The findings are an important step in development of a vaccine.
September 26, 2017 — The TMIST study is enrolling 165,000 women to compare 2-D and 3-D mammography for finding breast cancers. This NCI and ECOG-ACRIN press release describes the trial.
September 19, 2017 — They ranged in age from 15 to 61—four African American women, all with stories to tell about their struggles with sickle cell disease, all with stories about a common experience that helped them through those struggles: participating in clinical trials.
September 6, 2017 — Two scientists at the National Cancer Institute (NCI) will receive the 2017 Lasker-DeBakey Clinical Medical Research Award for their significant research leading to the development of human papillomavirus (HPV) vaccines.
August 7, 2017 — Elena Silva and Brian Woodward sought a diagnosis for their daughter, Gabriela, who had an unknown muscle disorder that left her limbs to appear “floppy.” Silva had a chance encounter at the Cure CMD networking event for researcher and families affected by rare neuromuscular disorders at the NIH’s Clinical Center that led to Gabriela’s diagnosis.
July 24, 2017 — An NCI-COG press release about the launch of a nationwide clinical trial that aims to match targeted treatments to pediatric cancers with specific genetic mutations.
