Supplements, Facts First: A Digital Adventure for Every Age Challenge
Supplements, Facts First: A Digital Adventure for Every Age Challenge
Simplifying Supplements, One Fact at a Time
The NIH Office of Dietary Supplements wants to reimagine how people learn about dietary supplements. ODS wants to transform NIH's trusted fact sheets into interactive digital experiences for everyone.
Phase 1 open until 04/06/2026 05:00 PM EST
Total cash prizes: $869,000
Overview
The Office of Dietary Supplements (ODS) at the National Institutes of Health (NIH) announces the "Supplements, Facts First: A Digital Adventure for Every Age" challenge. This competition aims to catalyze innovative multimedia strategies to transform static dietary supplement fact sheets into engaging digital experiences. It addresses a critical gap between evidenced-based supplement information and meaningful public engagement by incentivizing teams to develop prototypes using at least TWO of the following five modalities:
- Behavior Change and Health Information Apps – Mobile or web-based applications designed to influence health behaviors and/or increase awareness and access to accurate health information on dietary supplements. Examples include gamified health tracking or challenge apps, goal-setting tools, interactive fact-sheet–based info apps, and habit-building tools with nudges and reminders.
- Social Media Content – Short-form, visually appealing media optimized for platforms such as TikTok, Instagram, Facebook, and YouTube. Because TikTok is one of the most effective channels for reaching younger and diverse audiences, it is highlighted as a central focus. However, due to federal security restrictions, TikTok cannot be accessed or hosted on government-furnished equipment (GFE). Solvers must demonstrate how TikTok strategies can be designed, tested, and evaluated using non-GFE tools and methods, with final outputs provided in transferable formats (e.g., MP4 video files, storyboards, or platform-agnostic templates) that NIH can review and adapt without direct TikTok access.
- AI-Enabled Tools – Artificial intelligence-powered solutions that generate or personalize content for different audiences. This includes tools such as custom podcast creators, health information chatbots, and AI-driven personalization engines.
- Serialized Video & Broadcast Content – Long-form or episodic content for platforms like YouTube, streaming services, or TV that blends storytelling with evidence-based health information. Examples include docuseries, scripted episodes, animated explainers, or other episodic video formats that reinforce behavior change.
- Other Technology – Any other interactive technology supported by peer-reviewed literature demonstrating its ability to provide accurate health information and encourage healthy behavior change. Examples: Virtual Reality (VR) simulations immersing users in interactive nutrition and supplement-use scenarios; Augmented Reality (AR) overlays that scan supplement packaging to deliver fact-based guidance; SMS/text-based health coaching systems delivering reminders, fact checks, and prompts; voice-activated assistants (e.g. Alexa skills) to answer supplement questions using ODS facts; wearable device integrations providing prompts on supplement timing or interactions; interactive e-learning modules with quizzes and personalized feedback.
Target Audiences
Solutions must be tailored to 2 or more specific target audiences to ensure broad impact. Each submission must include at least: one age group (e.g. youth, adults, or older adults) and one special population experiencing health disparities (e.g. a group at high risk for chronic conditions, food-insecure families, veterans, new mothers). An additional target group (for a total of up to three) may be included as appropriate (for example, health professionals/clinicians or another community of interest), with a clear rationale based on evidence of need (such as data on supplement use or misinformation in that group).
Subject of the Challenge
NIH's Dietary Supplement Fact Sheets are the evidenced-based resource on dietary supplements and their ingredients. (Dietary supplements include vitamins, minerals, herbs, botanicals, probiotics, and more.) These evidence-based summaries provide information on the effectiveness, safety, and use of supplement ingredients for two primary audiences: health professionals and consumers. Some fact sheets are available in both English and Spanish, designed for broad audiences such as healthcare providers, caregivers, researchers, educators, and policymakers. However, the consumer versions of the ODS Dietary Supplement Fact Sheets are accessed significantly less than the health professional versions. In an environment of conflicting opinions and widespread misinformation about the benefits and safe use of supplements, a critical gap exists in consumer education. This challenge seeks to close that gap by supporting innovative, evidence-based communication platforms that improve public health literacy and promote safe, informed use of dietary supplements. In short, the challenge will translate static ODS fact sheets into innovative, multi-modal, culturally and linguistically tailored digital experiences that improve health literacy and support safe, informed decisions about supplements.
Three-Phase Structure
This is a three-phase challenge designed to integrate TWO OR MORE modalities and advance solutions from concept to real-world impact. Across the phases, teams are expected to deliver culturally and linguistically tailored digital experiences that measurably improve consumer supplement literacy, promote safe and informed supplement use, demonstrate strong usability and engagement, and produce implementation-ready solutions with preliminary evidence for scale and dissemination.
- Phase 1 – Concept Development (Community-Engaged Design): Solvers submit a Concept Paper describing their proposed solution and a detailed strategy for incorporating Community-Based Participatory Research (CBPR) principles to engage and tailor the approach for specific communities. Submissions must clearly outline: (a) the target demographic(s) and/or special populations at elevated risk for misinformation or poor supplement literacy; (b) the proposed modalities and how they will work together to improve understanding and promote safe supplement use; (c) the planned co-creation process with community stakeholders, including how stakeholder input will inform design; and (d) preliminary plans for evaluation, scalability, and sustainability. Participants can choose to further develop and prototype their solutions in Phase 2 but are not required to use their Phase 1 prize money for that purpose. Successful Phase 1 submissions (semi-finalists) will each receive an unrestricted cash prize. Winners may opt to advance their solutions in Phase 2, but this is not mandatory for using the prize money.
- Phase 2 – Prototype Development & Initial Validation: Selected Phase 1 teams (finalists) will create functional prototypes, conduct initial user testing, and refine their solutions based on community feedback and early evaluation data. This phase emphasizes technical feasibility, usability, and user engagement, with clear documentation of iterative improvements and validation processes.
- Phase 3 – Full Implementation, Pilot Testing & Evaluation: Finalists from Phase 2 will implement their fully developed, production-ready solutions in real-world settings, conduct a pilot test with their target audience(s), and complete a comprehensive evaluation of impact and scalability. This phase culminates in identifying high-impact solutions ready for broad dissemination.
Key Milestones and Dates
- Challenge Launch & Open Call: January 20, 2026
- Registration: Open from January 20, 2026 (teams may register any time before Phase 1 submission deadline)
- Phase 1 Period:
- Phase 1 Submission Deadline (Concept Paper): April 6, 2026
- Phase 1 Judging Period: April 7 – May 10, 2026
- Phase 1 Winners Announced: May 11, 2026 (up to 8 semi-finalist teams)
- Phase 2 Period:
- Phase 2 Prototype Development: May 12, 2026 – April 20, 2027
- Phase 2 Submission & Judging: April 21 – June 5, 2027
- Phase 2 Winners Announced: June 6, 2027 (up to 5 finalist teams; all receive awards)
- Phase 3 Period:
- Phase 3 Period (Full Implementation/Pilot): June 7, 2027 – December 6, 2027
- Phase 3 Midpoint Check-In: September 6, 2027 (progress review for Phase 3 teams)
- Phase 3 Judging Period: December 7, 2027 – January 19, 2028
- Grand Prize Winners Announced: January 20, 2028 (announcement of final winners)
- TOTAL CHALLENGE DURATION: 24 MONTHS
Summary
This phased structure invests early in promising concepts through community-informed design (Phase 1), builds and validates prototypes with user engagement (Phase 2), and reserves substantial awards for thoroughly tested, implementation-ready solutions (Phase 3).
Payment of the Prize:
Prizes awarded under this Challenge will be paid by electronic funds transfer and may be subject to federal income taxes. The Department of Health and Human Services (HHS)/NIH will comply with the Internal Revenue Service withholding and reporting requirements, where applicable.
Entities participating in this Challenge are encouraged, but not required, to request and obtain a free Unique Entity ID (UEI), if they have not already done so, via SAM.gov as this will expedite prize payment. Additional information can be found at https://sam.gov/content/entity-registration.
NIH reserves the right, in its sole discretion to: (a) cancel, suspend, or modify the Challenge, or any part of it, for any reason, and/or (b) not award any prizes if no submissions are deemed worthy.
Prizes
Total cash prizes: $869,000
Rules
Eligibility requirements
Eligibility Rules: To be eligible to win a prize under this Challenge, a participant (whether an individual, group of individuals, or entity) must meet the following requirements:
- Registration: The Participant must have registered to participate in the Challenge through the designated challenge website, in accordance with the rules published in this announcement.
- Compliance: The Participant must have complied with all requirements of this announcement.
- U.S. Presence: For a private entity, it must be incorporated in and maintain a primary place of business in the United States. For an individual (whether participating alone or in a team), the individual must be a U.S. citizen or a permanent resident of the U.S. (However, non-U.S. citizens and non-permanent residents may participate as members of an otherwise eligible team. They are not eligible to win a monetary prize themselves, though their contributions can be recognized in team awards.)
- Federal Employees: The Participant must not be a federal entity or a federal employee acting within the scope of their employment. (Federal employees of agencies other than HHS may participate in their personal capacity but should consult their ethics officials to ensure no conflict. Employees of HHS, or any component of HHS, may not participate.)
- Challenge Affiliates: The Participant must not be a Challenge judge, or any other party involved in design, production, execution, or administration of the Challenge (or an immediate family member of such a party).
- Age: The Participant (individual or team leader) must be 18 years of age or older at the time of submission.
Participation Rules
- Participants (individuals, teams, or organizations) may not use federal funds (grant money or federal contracts) to develop their Challenge submissions or to fund efforts in support of their submissions.
- Federal contractors may not use federal contract funds to develop or support their Challenge submission.
- By participating, each Participant agrees to assume all risks and waive claims against the federal government and its related entities for any injury, death, damage, or loss of property, revenue, or profits arising from participation in the Challenge. (The only exception is for claims of willful misconduct.)
- Based on the subject matter of the Challenge and the work it entails, and analysis of potential risks, participants are not required to obtain liability insurance, demonstrate financial responsibility, or indemnify the federal government to participate.
- A Participant will not be deemed ineligible for using federal facilities or consulting with federal employees during the Challenge, provided that such resources are made available to all participants on an equitable basis.
- By participating, each Participant warrants that they are the sole author or owner of (or have rights to use) any intellectual property in the submission, and that the submission does not infringe upon any third-party rights.
- By participating, each Participant grants NIH a nonexclusive, irrevocable, royalty-free, worldwide license to reproduce, publish, share, and publicly display their submission (or parts of it) for the purposes of administering or promoting the Challenge. Participants retain all other intellectual property rights. Participants further warrant that there are no legal obstacles to granting the above license to the federal government. No transfer of IP ownership is required to receive an award; winners grant the government the limited licenses described here.
- Participants must adhere to all applicable federal, state, and local laws, regulations, and policies. Participation in the Challenge constitutes the participant's full and unconditional agreement to abide by all rules of this competition. Winning is contingent upon fulfilling all requirements herein.
- As a condition of being awarded a prize, each winning Participant (individual or entity) must complete and submit all requested winner verification and payment documents to NIH within 10 business days of notification. Failure to return required documents by the specified date may result in the disqualification of that winner.
- Team Size: There is no minimum or maximum team size required; individual participants and teams of any size are eligible to compete
Judging
Phase 1 Evaluation Criteria (for Concept Phase—up to 8 semi-finalists)
Timeline: January 20, 2026 – April 6, 2026
- 1. Innovation & Technical Excellence (25%)
Is the concept creative and technically sound? Judges will assess the extent to which the solution transforms ODS fact sheet content into new, engaging formats spanning ≥2 modalities from the list above.
Objective Assessment Examples:- Does the solution present ODS information in formats that don't already exist?
- Are the technical connections between modalities clearly thought out?
- Is it feasible to build with existing tech?
- Audience Reach & Demographic Targeting (30%)
Does the concept effectively target the right people? Judges will look at how well-defined and justified the target audiences are and how the solution will reach them.
Objective Assessment Examples:- Are the target audiences well-supported by data (e.g., clearly documented needs or disparities)?
- How specifically do the sample content and distribution plans address each audience's needs?
- How concrete are the partnership commitments (specific support vs. vague interest)?
- Scientific Accuracy & Health-Impact Potential (25%)
Is the content accurate, and will it make a difference in health decisions? Submissions should demonstrate a commitment to evidence-based information and impactful outcomes.
Objective Assessment Examples:- What proportion of health-related statements in the concept are backed by ODS references?
- How specific and realistic are the proposed outcome targets?
- Are the chosen metrics appropriate to measure changes in supplement-related knowledge or behavior?
- User Engagement & Experience Design (20%)
Is the solution user-centered and engaging? Judges will evaluate how well the concept considers the user's journey and incorporates user feedback.
Objective Assessment Examples:- How complete is the depiction of the user experience (does it cover all major steps and decision points)?
- If user feedback was gathered, is it clearly integrated into the design?
- If not, is there a clear, specific plan for user testing? Are the cross-modality transitions well thought out and clear?
Phase 2 Evaluation Criteria (for Prototype Phase – up to 5 finalists)
Timeline: May 12, 2026 – April 20, 2027
- Implementation & Real-World Impact (35%)
Can the prototype be deployed, and does it show promise of real impact? Judges will look at evidence from the functional prototype and user testing.
Objective Assessment Examples:- What percentage of the team's target metrics were achieved?
- How many users did they end up testing with, and what was the completion rate?
- Do the outcomes measured correspond to safer supplement use or better decision-making?
- Scalability & Sustainability (25%)
Is the solution technically robust and ready to scale further? Judges will consider the technical performance and plans for future deployment.
Objective assessment examples:- Did the team conduct performance testing, and what were the results (e.g., how many users can handle it simultaneously)?
- Is there documentation of load times (was it under 5 seconds, under 10 seconds, etc.)?
- Did the team secure any formal agreements or letters for Phase 3 implementation sites?
- Community Integration (25%)
How well did the team engage community partners/users in Phase 2? Judges will look for evidence of ongoing community involvement and co-design.
Objective Assessment Examples:- How many feedback sessions did the team hold?
- Can they point to specific features or changes that were a direct result of community input?
- Did most partners who committed participate actively?
- Did community engagement occur early enough to influence the design (versus last-minute)?
- Innovation & Cross-Media Synergy (15%)
How well do the different modalities work together, and is the solution innovative? Judges will consider the degree of integration between modalities and overall creativity.
Objective Assessment Examples:- How many points of integration were implemented and verified (e.g., app ↔ social media, chatbot ↔ video content)?
- What percentage of test users utilized more than one modality?
- Is there documentation or a demo to prove data passes between modalities (for instance, a user's progress in a game influences the recommendations in the chatbot)?
Phase 3 Evaluation Criteria (for Final Phase – Grand Prize selection among finalists)
Timeline: June 7, 2027 – December 6, 2027
- Sustained Real-World Impact (30%)
Did the solution produce real, measurable impacts during the pilot? Judges will examine results from the Phase 3 pilot implementation.
Objective Assessment Examples:- How long did the pilot run?
- What measured changes were seen (knowledge scores, behavior changes, etc.), and how large were they?
- What proportion of participants stayed for the whole pilot period?
- Did the pilot stay on schedule?
- Innovation & Technical Excellence (30%)
Did the solution maintain technical quality and continue to improve throughout the pilot? Judges will look at how the system performed and improved over the 6 months.
Objective Assessment Examples:- What was the actual uptime percentage, and did it meet 95%?
- How many of the 50+ WCAG AA accessibility criteria did the final solution comply with?
- How many updates or fixes were made over the pilot period to improve the product?
- Audience Reach & CBPR Alignment (20%)
Did the project achieve its reach goals and uphold its community-engagement commitments?
Objective Assessment Examples:- What percentage of the intended participant number was enrolled?
- How many CAB or advisory meetings took place and had a quorum?
- What percentage of pilot participants came from the intended underserved communities?
- Cross-Media Synergy & UX (20%)
What was the user feedback and engagement across platforms in the pilot? This category looks at user satisfaction and multi-platform engagement at scale.
Objective Assessment Examples:- What was the calculated NPS score from pilot participants?
- How many unique users actively used the solution in the final month?
- How many users engaged with more than one modality (indicating they experienced the cross-media aspect)?
- Scalability, Sustainability, Adoption Readiness — BONUS POINTS CATEGORY
Solutions are judged primarily on pilot impact (criteria 1-4). Strong sustainability plans enhance scores but are not required for Grand Prize consideration.
Is the solution ready to be adopted and scaled after the challenge? Judges will consider how well the team prepare for life after the challenge.
Objective Assessment Examples:- How many organizations formally committed to exploring or supporting the solution after the challenge?
- Did the team provide a full toolkit or set of documentation for others to use? Are those resources accessible (e.g., posted online)?
- Is there evidence that the solution can be maintained or expanded beyond the pilot?
How to enter
Registration
Participants must register for the challenge on the official challenge website (link to be provided on launch). Registration opens on January 20, 2026. Teams may register at any time before submitting their Phase 1 concept paper (due April 6, 2026). During registration, basic information (team name, participant names, contact info) and acceptance of the rules will be required. Upon registration, participants will receive access to the full challenge platform, resources, and any updates (such as FAQs and workshop details).
Phase 1 Submission
All Phase 1 Concept Development submissions are due by April 6, 2026, 5:00 PM ET via the challenge submission portal. Teams should submit the required materials (described below) according to the instructions on the portal (acceptable file formats, size limits, etc., will be provided on the site). Submissions must be in English. Only one submission per team is allowed for Phase 1. There is no fee to enter.
Required Deliverables – Phase 1 (Concept Phase)
- Concept Paper – A written proposal, ≤10 pages (PDF format), describing the vision and goals of the solution, the 2–3 target groups it will address (with justification), the selected modalities and how they will integrate, and high-level plans for Phase 2 evaluation and Phase 3 implementation/sustainability. This document should include any figures or tables necessary (within the page limit). Use the NIH-provided template to streamline development.
- Concept Demonstrations – Illustrative media demonstrating the concept across ≥2 modalities. This can include mockups, wireframes, illustrations, or storyboarded videos. Up to 6 total minutes of media are allowed (e.g., a 3-minute demo for each modality if using 2). These demos do not need to be polished or fully functional; simple prototypes or even slides/videos capturing the envisioned user experience are acceptable in Phase 1.
- Demographic Customization Samples – At least one example of tailored content for each target audience identified. For instance, if older adults and new mothers are target groups, provide a sample of how the content or approach is tailored to each group. (This may overlap with the concept demos or be described in the concept paper.)
- User Engagement Plan – Either evidence of informal user feedback already gathered (notes from 5–10 potential users or community members about the concept), OR a Phase 2 testing plan detailing how the team would test the prototype with users (specify target number of testers, e.g. 15–40, and methods like surveys or interviews, and include any planned usability metrics such as SUS). This element is to demonstrate a user-centered mindset.
- Team & Partners – A description of team composition and any confirmed partners. Include the roles/expertise of key team members and at least 1 letter of intent (LOI) or Memorandum of Understanding (MOU) from a community partner or organization that has agreed to support the project (e.g., assisting with content co-creation, user recruitment, or dissemination). (The 2nd partner can be added in Phase 2.) Also, please attach brief resumes/bios for core team members (each ≤ 1 page). The letters can count as appendices (not part of the 10-page concept paper limit). Use NIH-provided partnership agreement templates.
Important Note (Phase 1): Working software/code is NOT required in Phase 1. Solvers may submit mock-ups, sketches, and conceptual prototypes. Focus Phase 1 efforts on concept development, user journey mapping, and partnership building rather than programming. The judging will place value on the creativity, evidence-based, and community engagement plan behind the concept. Fully functional prototypes will be developed in Phase 2 for those who advance.
Phase 2 Submission
Only the Phase 1 winners (semi-finalists) are eligible to participate in Phase 2. Phase 2 submissions will be due April 20, 2027, at 5:00 PM ET. Detailed submission instructions will be provided for finalists, but in general, Phase 2 deliverables include:
- Functional Multi-Modal Prototype – An integrated, working demonstration of the solution incorporating the chosen modalities. (It need not be a public-ready or polished product, but it should be sufficiently functional to test with users and demonstrate key features.)
- User Study Results – Documentation of the initial user testing conducted (target 15–40 users). Include usability metrics (e.g., SUS or UMUX-Lite scores with benchmarks), knowledge gains or other outcome measures, and any usage analytics or feedback collected. Summarize what was learned and what iterative changes were made during Phase 2.
- Technical Documentation – A brief technical report OR ≤10-minute video walkthrough describing the prototype's architecture and performance. Include information on how many concurrent users the system was tested with (and results, e.g., supported ~15 users with no crashes), observed load times (e.g., average <5–10 seconds), and a plan for Phase 3 implementation (what needs to be done to go from prototype to pilot scale).
- Community Integration Report – Description of how partners and community feedback were integrated in Phase 2. Document at least 1–2 feedback sessions or user/community workshops held, what feedback was obtained, and how it influenced the prototype. Outline the Phase 3 community engagement plan (e.g., establishing a Community Advisory Board and recruitment strategies for the pilot).
Phase 2 submissions will be judged in June 2027, and up to 5 finalists will receive awards. Top performers will advance to Phase 3.
Phase 3 Submission
Only Phase 2 top performers advance to Phase 3. Phase 3 final submissions will be due December 6, 2027 at 5:00 PM ET. Phase 3 deliverables will include:
- Final Integrated Solution – The fully operational multi-modal solution (production-ready prototype) with all components integrated. This should be accompanied by any necessary training manuals or user guides to operate the solution.
- Pilot Implementation Report – Documentation of the Phase 3 pilot deployment. Include details on pilot setting(s) (1–2 sites), number of participants (target 20–100), with demographics), duration (3–6 months), and any IRB or ethical oversight obtained. Provide the outcomes of the pilot: pre/post evaluations, qualitative feedback, retention data, and any measurable effect sizes (e.g., improvements observed).
- Scalability & Sustainability Brief – At least a 3-page summary (+ optional appendices) outlining how the solution can be scaled and sustained beyond the challenge. This should include an implementation toolkit (or its description) that was developed, any confirmed interest from external organizations (conditional letters acceptable) (attach at least one letter of interest from an organization willing to adopt or support the solution), and a proposed business or operational model for future deployment. EVALUATED FOR BONUS POINTS; NOT REQUIRED FOR GRAND PRIZE.
- Community Engagement Summary – A report on the community partnership aspect in Phase 3. Document the formation and activities of the Community Advisory Board or equivalent advisory group: number of meetings (at least 2), key feedback or guidance provided, and how that input led to adaptations. Include any testimonials or statements from partners/community members on the collaboration.
- Dissemination-Ready Materials (optional) – Teams may include a short "elevator pitch" video or infographic (1–2 minutes or a one-pager) summarizing their solution's impact, which NIH can use for promotion or by the team to seek further adoption. (This is optional but recommended for winners.)
All Phase 3 submissions will be evaluated from December 2027 to January 2028 to select the Grand Prize winner, Runner-up, and Third Place.
Contact
HeroX: www.herox.com/SupplementsFactsFirst
Email: gethelp@herox.com
Winners
Winners will be announced following judging of submissions.
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