20241112-RAS-schematic.jpg

illustration of RAS protein activity

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illustration of RAS protein activity

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Mutant RAS helps release EZH2 from a protein complex transported from the nucleus to the cytoplasm. Once released, EZH2 facilitates the breakdown of the DLC1 tumor suppressor protein, leading to uncontrolled tumor growth.

Credit

NCI via biorender.com

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illustration of RAS protein activity
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illustration of RAS protein activity