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NIH Research Matters

October 6, 2014

Pregnant woman touching her belly and sitting at her desk.

More Knowledge Reduces Prenatal Testing

Pregnant women given computer-based information about prenatal screening were more likely to skip testing, especially invasive tests—even when the tests were free.

Prevotella

Diet Affects Autoinflammatory Disease Via Gut Microbes

A study in mice revealed how diet-induced changes to intestinal bacteria can influence autoinflammatory disease. The results could guide new approaches to these diseases.

Mutant AGT and peroxisomes together in a cell treated with DECA.

Compound Fixes Problem Seen in Rare Kidney Disease

In a proof-of-principle study, scientists identified a compound that can correct a cellular defect that causes a rare kidney disease.

September 29, 2014

Zebrafish

How Genes Affect Facial Development

A zebrafish study shed light on how the structure of the face forms. Problems with equivalent genes in people can cause facial defects and other developmental issues.

The fibrin mesh of a blood clot.

Microgel Particles Boost Blood Clotting

Researchers developed microgel particles that mimic platelets and help form blood clots. The approach could lead to new treatments for uncontrolled bleeding.

Bacteriophage

Method Can Target Specific Microbes

Scientists designed a way to target and destroy specific DNA sequences in microbes. The approach might one day be used against pathogenic bacteria resistant to multiple antibiotics.

September 22, 2014

A fruit fly.

Fruit Flies Yield Insights Into Aging

Activating certain molecules in key tissues slowed aging in fruit flies. The findings could lead to a better understanding of aging processes in people.

A womanís shoulder muscles.

Controlling Muscle Repair

By manipulating a protein called Stat3, researchers regenerated muscle in mice. The approach may point the way to treatments for muscle-wasting diseases.

Cells moving in different ways.

New Mechanism of Cell Movement Revealed

Researchers described how a cellís nucleus can act as a piston to propel it through a 3-D matrix. The findings may help in the design of strategies to regenerate tissue and inhibit metastatic cells.

September 15, 2014

Colorized scanning electron micrograph of Ebola virus particles (green) attached to and budding from a cell (blue).

Genetics of the 2014 Ebola Outbreak

Scientists used genomic sequencing technologies to identify the origin and track transmission of the Ebola virus in the current outbreak in Africa.

Illustration of fruit flies, people, and roundworms.

Expanding Our Understanding of Genomics

By analyzing the genomes of humans, flies, and worms, scientists are gaining insights into complex biological processes that are vital to human biology and disease.

Cells in mouse hearts.

Molecule Protects Against Heart Failure in Mice

Researchers identified a molecule that plays a role in heart failure in mice. The findings may lead to a new therapeutic agent to treat this common condition.

August 25, 2014

A female Anopheles gambiae mosquito feeding on a human.

Drug Prevents Malaria in High-Risk Region

A combination drug treatment substantially reduced malaria in young children in Africa. The treatment could help reduce the disease burden among those most at risk.

Person getting an injection.

Chikungunya Vaccine Shows Promise

A chikungunya vaccine gave encouraging results in an early-stage clinical trial. A vaccine could prevent outbreaks of the disease, which recently reached the U.S. mainland.

Glutamate receptor

Structural States of a Brain Receptor Revealed

Scientists determined the detailed structural states of the glutamate receptor, which is involved in learning, memory, and several diseases.

August 18, 2014

Blurred image of person walking toward camera.

Over 100 Genetic Sites Tied to Schizophrenia

Researchers found 108 genetic regions linked to schizophrenia, including 83 previously unrecognized. The findings suggest new avenues for potential treatments.

Inflamed blood vessels

Gene Linked to Rare Inflammatory Disease in Children

Scientists identified a gene that underlies a rare but devastating autoinflammatory condition in children. The study suggests a potential treatment for this and related diseases.

Brain tissue of a CJD patient

Detecting Human Prion Disease

New tests rapidly and accurately diagnose Creutzfeldt-Jakob disease, an incurable and ultimately fatal neurodegenerative disorder. Such tests would have important clinical and research uses.

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About NIH Research Matters

Editor: Harrison Wein, Ph.D.
Assistant Editors: Vicki Contie, Carol Torgan, Ph.D.

NIH Research Matters is a weekly update of NIH research highlights from the Office of Communications and Public Liaison, Office of the Director, National Institutes of Health.

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This page last reviewed on October 6, 2014

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