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NIH Research Matters

NIH Research Matters May 2010 Archive

May 24, 2010

Electron micrograph of crescent-shaped sickle cell among rounded blood cells.

Sickle Cell Disease May Affect Brain Function

Adults who have mild sickle cell disease scored lower than healthy participants on tests of brain function, suggesting that the blood disease may affect the brain more than previously realized. The new study is the first to examine cognitive functioning in adults with sickle cell disease.

Photo of twin infants.

Landmark Analysis Probes Nature vs. Nurture in Multiple Sclerosis

After an extensive genetic analysis, researchers were still unable to account for why, in 3 pairs of identical twins, one twin in each developed multiple sclerosis (MS) while the other didn't. The study represents the first female, twin and autoimmune disease genome sequences ever reported. The study doesn't question whether genes contribute to MS, but it strengthens the idea that environmental factors play an important role.

Photo of Dr. Svante Pääbo holding a Neanderthal skull.

Neanderthal Genome Sequenced

Researchers have produced the first whole-genome sequence of the Neanderthal genome. The analysis provides the first genome-wide look at the similarities and differences of the closest evolutionary relative to humans.

May 10, 2010

Photo of eye with yellow spots near dark macula at the center.

Study Confirms New Treatment for Diabetic Macular Edema

Researchers have found that eye injections of a medication, in combination with laser treatment, result in better vision than laser treatment alone for diabetes-associated swelling of the retina.

Photo of hands holding a medicine vial and a DNA label.

Patient's Whole Genome Reveals Disease and Medication Risks

Scientists have evaluated the entire genome of a 40-year-old man to determine his risk for dozens of diseases and his likely response to several common drugs. The study provides a glimpse of how whole-genome sequencing might one day be used in the clinic.

Photo of Xenopus tropicalis.

First Frog Genome Sequenced

Researchers published a draft genome of the western clawed frog Xenopus tropicalis—the first amphibian genome to be sequenced. The accomplishment will not only yield insights into evolution; it could also lead to a better understanding of many human diseases.

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About NIH Research Matters

Editor: Harrison Wein, Ph.D.
Assistant Editors: Vicki Contie, Carol Torgan, Ph.D.

NIH Research Matters is a weekly update of NIH research highlights from the Office of Communications and Public Liaison, Office of the Director, National Institutes of Health.

ISSN 2375-9593

This page last reviewed on December 4, 2012

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