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NIH Research Matters

April 20, 2015

HIV-infected immune cells.

HIV Immunotherapy Promising in First Human Study

An experimental antibody significantly reduced HIV levels in infected people for as long as 28 days. The approach might help to combat a wide range of HIV strains.

3d rendered illustration of hepatitis virus.

Allergy Drug Treats Hepatitis C in Mice

A common over-the-counter allergy drug lowered hepatitis C virus levels in infected mice. The drug is currently being tested in patients with chronic hepatitis C.

Schematic map showing the 4 sites occupied by borrelidin.

Scientists Discover Antibiotic Mechanism

A structural study revealed how an antibiotic called borrelidin stops bacterial growth. The findings may help researchers design improved drugs to fight infections.

April 13, 2015

Ebola virus.

Ebola Vaccine Candidate Promising in Early Study

An experimental Ebola vaccine called VSV-ZEBOV was safe and produced robust antibody responses in all the healthy adults who received it. Itís now being tested in Liberia.

Illustration of the lymphatic system.

Tumor DNA in Blood Reveals Lymphoma Progression

Using an advanced genetic test, researchers detected diffuse large B-cell lymphoma in blood before it could be seen on CT scans. The technique could improve disease monitoring.

Beige fat cells.

Insights into Energy-Burning Fat Cells

Researchers identified beige fat cells, which burn energy rather than store it, in humans. The finding may lead to new ways to engineer fat cells to fight obesity.

March 30, 2015

Dendritic cell.

Boosting Immunotherapy Against Brain Cancer

Researchers used a tetanus booster to enhance the effects of an experimental immunotherapy against glioblastoma, a deadly type of brain cancer.

Woman consulting with her doctor.

Interpreting Breast Biopsies

Pathologists asked to interpret a difficult set of breast biopsy slides accurately made most diagnoses, but the results suggest strategies for future improvement.

Illustration of white blood cells.

How Vitamin D May Affect Heart Disease, Diabetes

Mice with immune cells unable to use vitamin D developed precursors of heart disease and type 2 diabetes. The mechanisms uncovered may lead to novel therapies.

March 23, 2015

Illustration of DNA, blood cells, and a blood vessel.

Genetics Help Predict Heart Disease Risk, Statin Benefits

Researchers found that a set of genetic variants could identify people at risk for coronary heart disease and who would benefit most from statin therapy.

Healthy older cyclists.

Physical Activity May Reduce Age-Related Movement Problems

Physical activity may help improve movement problems linked to brain lesions in older people. The results highlight the importance of an active lifestyle for older adults.

Illustration of cells in a tumor.

Novel Approach Gives Insights Into Tumor Development

Scientists used a powerful new technique to systematically turn off all the genes in mouse lung cancer cells and test how they affect tumor growth and metastasis.

March 16, 2015

Teenage boy and girl on inline skates.

Cleaner Air Tied to Healthier Lungs in Kids

Falling air pollution levels in Southern California were associated with improvements in childrenís lung function during a critical period of growth and development.

Bacteria in mouse intestine.

Food Additives Alter Gut Microbes, Cause Diseases in Mice

A study in mice suggests that common food additives called emulsifiers might play a role in the increasing incidence of obesity and chronic inflammatory bowel disease.

Human T cell

Autoimmune Disease Super-Regulators Uncovered

Genetic switches called super-enhancers help regulate the human immune system. The finding will inform research into autoimmune disorders such as rheumatoid arthritis.

March 9, 2015

Girl eating peanut butter sandwich.

Peanut Consumption in Infancy Lowers Peanut Allergy

Infants who regularly consumed peanut products from infancy to age 5 proved less likely to become allergic to peanuts.

Graphic representation of epigenomic data sets.

Human Epigenome Map Yields Insights into Development, Disease

More than 100 reference human epigenomes from a broad range of cell and tissue types revealed epigenomic factors associated with age, sex, tissue type, and various diseases.

HIV envelope protein binding sites.

Compound May Protect Against HIV

Scientists created a compound that could potentially lead to a long-lasting method of HIV prevention and treatment.

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About NIH Research Matters

Editor: Harrison Wein, Ph.D.
Assistant Editors: Vicki Contie, Carol Torgan, Ph.D.

NIH Research Matters is a weekly update of NIH research highlights from the Office of Communications and Public Liaison, Office of the Director, National Institutes of Health.

ISSN 2375-9593

Research News from NIH and Grantees

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This page last reviewed on April 20, 2015

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