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<title>NIH Research Matters from the National Institutes of Health (NIH)</title>
<description>A weekly summary of research developments and discoveries at NIH</description>
<language>en-us</language>
<link>http://www.nih.gov/researchmatters/index.htm</link>
<managingEditor>weinh@od.nih.gov</managingEditor>
<lastBuildDate>Mon, 08 Dec 2008 09:00:00 EDT</lastBuildDate>

<image>
<title>National Institutes of Health (NIH) Logo</title> 
<url>http://www.nih.gov/images/nih50.gif</url> 
<link>http://www.nih.gov/researchmatters/index.htm</link> 
<width>50</width> 
<height>50</height> 
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<!-- The week of May 14, 2012 -->
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<title>Test Before Incontinence Surgery Often Unnecessary</title>
<description>&lt;p&gt;&lt;a href=&quot;http://www.nih.gov/researchmatters/may2012/05142012incontinence.htm&quot;&gt;&lt;img src=&quot;http://www.nih.gov/researchmatters/may2012/images/incontinence_th.jpg&quot; align=&quot;left&quot; height=&quot;72&quot; width=&quot;72&quot; alt=&quot;Photo of a woman sitting in a waiting room." alt="Photo of a woman sitting in a waiting room.=&quot;0&quot; /&gt;&lt;/a&gt;
A routine bladder function test given to women before urinary incontinence surgery may be unnecessary, a new study reports. 
&lt;/p&gt;&lt;br clear="all"/&gt; </description> 
<pubDate>Mon, 14 May 2012 10:00:00 EDT</pubDate>
<link>http://www.nih.gov/researchmatters/may2012/05142012incontinence.htm</link>
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<title>Mental Replay in Learning and Memory</title>
<description>&lt;p&gt;&lt;a href=&quot;http://www.nih.gov/researchmatters/may2012/05142012replay.htm&quot;&gt;&lt;img src=&quot;http://www.nih.gov/researchmatters/may2012/images/replay_th.jpg&quot; align=&quot;left&quot; height=&quot;72&quot; width=&quot;72&quot; alt=&quot;Microscope image of a network of branched neurons with pyramid-shaped cell bodies." alt=Microscope image of a network of branched neurons with pyramid-shaped cell bodies.=&quot;0&quot; /&gt;&lt;/a&gt;
A study in rats suggests that the mental replay of an experience is essential for making informed decisions. The work brings researchers closer to understanding how memories are represented and used by the brain.
 &lt;/p&gt;&lt;br clear="all"/&gt; </description> 
<pubDate>Mon, 14 May 2012 10:00:00 EDT</pubDate>
<link>http://www.nih.gov/researchmatters/may2012/05142012replay.htm</link>
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<title>Chromosome Quirks Linked to Aging and Cancer</title>
<description>&lt;p&gt;&lt;a href=&quot;http://www.nih.gov/researchmatters/may2012/05142012chromosome.htm&quot;&gt;&lt;img src=&quot;http://www.nih.gov/researchmatters/may2012/images/chromosome_th.jpg&quot; align=&quot;left&quot; height=&quot;72&quot; width=&quot;72&quot; alt=&quot;Illustration of chromosomes." alt="Illustration of chromosomes.=&quot;0&quot; /&gt;&lt;/a&gt;
Large structural abnormalities in chromosomes become more common with age and may be linked to increased risk for cancer. The new findings offer insights into how cancer and other disorders might emerge as people get older.

&lt;/p&gt;&lt;br clear="all"/&gt; </description> 
<pubDate>Mon, 14 May 2012 10:00:00 EDT</pubDate>
<link>http://www.nih.gov/researchmatters/may2012/05142012chromosome.htm</link>
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<!-- The week of May 07, 2012 -->
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<title>Treating Type 2 Diabetes in Youth</title>
<description>&lt;p&gt;&lt;a href=&quot;http://www.nih.gov/researchmatters/may2012/05072012diabetes.htm&quot;&gt;&lt;img src=&quot;http://www.nih.gov/researchmatters/may2012/images/diabetes_th.jpg&quot; align=&quot;left&quot; height=&quot;72&quot; width=&quot;72&quot; alt=&quot;Photo of a young teenage girl." alt="Photo of a young teenage girl.=&quot;0&quot; /&gt;&lt;/a&gt;
A combination of 2 diabetes drugs, metformin and rosiglitazone, was more effective in treating youth with type 2 diabetes than metformin alone, according to a new study. &lt;/p&gt;&lt;br clear="all"/&gt; </description> 
<pubDate>Mon, 07 May 2012 10:00:00 EDT</pubDate>
<link>http://www.nih.gov/researchmatters/may2012/05072012diabetes.htm</link>
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<title>Drugs Equally Effective for Age-Related Vision Loss</title>
<description>&lt;p&gt;&lt;a href=&quot;http://www.nih.gov/researchmatters/may2012/05072012vision.htm&quot;&gt;&lt;img src=&quot;http://www.nih.gov/researchmatters/may2012/images/vision_th.jpg&quot; align=&quot;left&quot; height=&quot;72&quot; width=&quot;72&quot; alt=&quot;Photo of a senior man's eye." alt=Photo of a senior man's eye.=&quot;0&quot; /&gt;&lt;/a&gt;
A comparison showed that the drugs Avastin and Lucentis lead to similar vision improvements in patients with age-related macular degeneration. Treatments given monthly were slightly more effective than when given as-needed. &lt;/p&gt;&lt;br clear="all"/&gt; </description> 
<pubDate>Mon, 07 May 2012 10:00:00 EDT</pubDate>
<link>http://www.nih.gov/researchmatters/may2012/05072012vision.htm</link>
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<title>Bilingual Effects in the Brain</title>
<description>&lt;p&gt;&lt;a href=&quot;http://www.nih.gov/researchmatters/may2012/05072012bilingual.htm&quot;&gt;&lt;img src=&quot;http://www.nih.gov/researchmatters/may2012/images/bilingual_th.jpg&quot; align=&quot;left&quot; height=&quot;72&quot; width=&quot;72&quot; alt=&quot;Photo of a teenage girl listening to a friend in a noisy cafeteria." alt="Photo of a teenage girl listening to a friend in a noisy cafeteria.=&quot;0&quot; /&gt;&lt;/a&gt;
A new study found certain brain functions that are enhanced in teens who are fluent in more than one language. The finding gives new insight into how our senses help shape our brains.&lt;/p&gt;&lt;br clear="all"/&gt; </description> 
<pubDate>Mon, 07 May 2012 10:00:00 EDT</pubDate>
<link>http://www.nih.gov/researchmatters/may2012/05072012bilingual.htm</link>
</item>

<!-- The week of April 30, 2012 -->
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<title>Device Restores Movement to Paralyzed Limbs</title>
<description>&lt;p&gt;&lt;a href=&quot;http://www.nih.gov/researchmatters/april2012/04302012movement.htm&quot;&gt;&lt;img src=&quot;http://www.nih.gov/researchmatters/april2012/images/movement_th.jpg&quot; align=&quot;left&quot; height=&quot;72&quot; width=&quot;72&quot; alt=&quot;Microscope image of branched motor neurons." alt="Microscope image of branched motor neurons.=&quot;0&quot; /&gt;&lt;/a&gt;
Monkeys paralyzed from the elbow down to their fingers were able to manipulate a ball with the help of an artificial connection between the brain and hand muscles. The technology might one day help paralysis victims regain muscle control.&lt;/p&gt;&lt;br clear="all"/&gt; </description> 
<pubDate>Mon, 30 Apr 2012 10:00:00 EDT</pubDate>
<link>http://www.nih.gov/researchmatters/april2012/04302012movement.htm</link>
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<item>
<title>Insights into MRSA Epidemic</title>
<description>&lt;p&gt;&lt;a href=&quot;http://www.nih.gov/researchmatters/april2012/04302012MRSA.htm&quot;&gt;&lt;img src=&quot;http://www.nih.gov/researchmatters/april2012/images/MRSA_th.jpg&quot; align=&quot;left&quot; height=&quot;72&quot; width=&quot;72&quot; alt=&quot;Photo of a Chinese female doctor using a microscope in a laboratory" alt="Photo of a Chinese female doctor using a microscope in a laboratory=&quot;0&quot; /&gt;&lt;/a&gt;
Scientists identified a gene that's been playing a pivotal role in epidemic waves of methicillin-resistant Staphylococcus aureus (MRSA) infections in Asia. The finding suggests a promising target for novel therapeutics.&lt;/p&gt;&lt;br clear="all"/&gt; </description> 
<pubDate>Mon, 30 Apr 2012 10:00:00 EDT</pubDate>
<link>http://www.nih.gov/researchmatters/april2012/04302012MRSA.htm</link>
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<title>Compound Points to Potential Autism Therapy</title>
<description>&lt;p&gt;&lt;a href=&quot;http://www.nih.gov/researchmatters/april2012/04302012autism2.htm&quot;&gt;&lt;img src=&quot;http://www.nih.gov/researchmatters/april2012/images/autism2_th.jpg&quot; align=&quot;left&quot; height=&quot;72&quot; width=&quot;72&quot; alt=&quot;Photo of a mouse sniffing another in a cage." alt="Photo of a mouse sniffing another in a cage.=&quot;0&quot; /&gt;&lt;/a&gt;
An experimental compound reversed certain autism-like behaviors in mice. The research may lead to a new strategy for treating autism spectrum disorders&lt;/p&gt;&lt;br clear="all"/&gt; </description> 
<pubDate>Mon, 30 Apr 2012 10:00:00 EDT</pubDate>
<link>http://www.nih.gov/researchmatters/april2012/04302012autism2.htm</link>
</item>


<!-- The week of April 23, 2012 -->
<item>
<title>Genetics of Bone Density</title>
<description>&lt;p&gt;&lt;a href=&quot;http://www.nih.gov/researchmatters/april2012/04232012bone.htm&quot;&gt;&lt;img src=&quot;http://www.nih.gov/researchmatters/april2012/images/bone_th.jpg&quot; align=&quot;left&quot; height=&quot;72&quot; width=&quot;72&quot; alt=&quot;x-ray of lumbar spine" alt="x-ray of lumbar spine=&quot;0&quot; /&gt;&lt;/a&gt;
A new study linked 32 novel genetic regions to bone mineral density. The findings may help researchers better understand bone fracture risk. They also suggest potential drug targets for preventing or treating osteoporosis.&lt;/p&gt;&lt;br clear="all"/&gt; </description> 
<pubDate>Mon, 23 Apr 2012 11:00:00 EDT</pubDate>
<link>http://www.nih.gov/researchmatters/april2012/04232012bone.htm</link>
</item>

<item>
<title>Clues to Emerging Drug-Resistant Malaria</title>
<description>&lt;p&gt;&lt;a href=&quot;http://www.nih.gov/researchmatters/april2012/04232012malaria.htm&quot;&gt;&lt;img src=&quot;http://www.nih.gov/researchmatters/april2012/images/malaria_th.jpg&quot; align=&quot;left&quot; height=&quot;72&quot; width=&quot;72&quot; alt=&quot;Photo of young girl." alt="Photo of young girl.=&quot;0&quot; /&gt;&lt;/a&gt;
Researchers report that a first-line treatment for malaria is losing its effectiveness in parts of Asia. They've also found parts of the parasite's genome that may underlie its drug resistance.&lt;/p&gt;&lt;br clear="all"/&gt; </description> 
<pubDate>Mon, 23 Apr 2012 11:00:00 EDT</pubDate>
<link>http://www.nih.gov/researchmatters/april2012/04232012malaria.htm</link>
</item>

<item>
<title>Molecular Effects of Social Stress</title>
<description>&lt;p&gt;&lt;a href=&quot;http://www.nih.gov/researchmatters/april2012/04232012social.htm&quot;&gt;&lt;img src=&quot;http://www.nih.gov/researchmatters/april2012/images/social_th.jpg&quot; align=&quot;left&quot; height=&quot;72&quot; width=&quot;72&quot; alt=&quot;Two rhesus macaques." alt="Two rhesus macaques.=&quot;0&quot; /&gt;&lt;/a&gt;
Social rank has broad effects on gene regulation, particularly in the immune system, according to a new study in rhesus macaques. The findings help explain how social status gets under your skin.&lt;/p&gt;&lt;br clear="all"/&gt; </description> 
<pubDate>Mon, 23 Apr 2012 11:00:00 EDT</pubDate>
<link>http://www.nih.gov/researchmatters/april2012/04232012social.htm</link>
</item>


<!-- The week of April 16, 2012 -->
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<title>Spontaneous Mutations Raise Autism Risk</title>
<description>&lt;p&gt;&lt;a href=&quot;http://www.nih.gov/researchmatters/april2012/04162012autism.htm&quot;&gt;&lt;img src=&quot;http://www.nih.gov/researchmatters/april2012/images/autism_th.jpg&quot; align=&quot;left&quot; height=&quot;72&quot; width=&quot;72&quot; alt=&quot;Photo of boy playing with toy block." alt="Photo of boy playing with toy block.=&quot;0&quot; /&gt;&lt;/a&gt;
New studies reveal several genes and biological pathways that may contribute to autism spectrum disorders. Among other insights, the findings may help explain earlier evidence linking autism risk to older fathers.&lt;/p&gt;&lt;br clear="all"/&gt; </description> 
<pubDate>Mon, 16 Apr 2012 11:00:00 EDT</pubDate>
<link>http://www.nih.gov/researchmatters/april2012/04162012autism.htm</link>
</item>

<item>
<title>Summer Temperature Swings Linked to Shorter Lifespan</title>
<description>&lt;p&gt;&lt;a href=&quot;http://www.nih.gov/researchmatters/april2012/04162012summer.htm&quot;&gt;&lt;img src=&quot;http://www.nih.gov/researchmatters/april2012/images/summer_th.jpg&quot; align=&quot;left&quot; height=&quot;72&quot; width=&quot;72&quot; alt=&quot;Photo of older man with blazing sun." alt="Photo of older man with blazing sun.=&quot;0&quot; /&gt;&lt;/a&gt;
Fluctuations in daily summer temperatures may boost the risk of death in older people with chronic diseases, according to a new study. The finding could have important implications for the nation's aging population.
&lt;/p&gt;&lt;br clear="all"/&gt; </description> 
<pubDate>Mon, 16 Apr 2012 11:00:00 EDT</pubDate>
<link>http://www.nih.gov/researchmatters/april2012/04162012summer.htm</link>
</item>

<item>
<title>Clues to HIV Protection</title>
<description>&lt;p&gt;&lt;a href=&quot;http://www.nih.gov/researchmatters/april2012/04162012hiv.htm&quot;&gt;&lt;img src=&quot;http://www.nih.gov/researchmatters/april2012/images/hiv_th.jpg&quot; align=&quot;left&quot; height=&quot;72&quot; width=&quot;72&quot; alt=&quot;Microscope image of round virus near a cell surface." alt="Microscope image of round virus near a cell surface.fat.=&quot;0&quot; /&gt;&lt;/a&gt;A new study gives insight into the workings of the first vaccine ever reported to modestly prevent HIV infection in people.&lt;/p&gt;&lt;br clear="all"/&gt; </description> 
<pubDate>Mon, 16 Apr 2012 11:00:00 EDT</pubDate>
<link>http://www.nih.gov/researchmatters/april2012/04162012hiv.htm</link>
</item>


<!-- The week of April 09, 2012 -->
<item>
<title>Genetics of a Tropical Foot Disease</title>
<description>&lt;p&gt;&lt;a href=&quot;http://www.nih.gov/researchmatters/april2012/04092012foot.htm&quot;&gt;&lt;img src=&quot;http://www.nih.gov/researchmatters/april2012/images/foot_th.JPG&quot; align=&quot;left&quot; height=&quot;72&quot; width=&quot;72&quot; alt=&quot;Photo of adnormally swollen feet." alt="Photo of adnormally swollen feet.=&quot;0&quot; /&gt;&lt;/a&gt;Researchers have identified gene variants that boost the risk for a debilitating tropical foot disease. The findings help shed light on how interactions between genes and the environment influence susceptibility to disease.&lt;/p&gt;&lt;br clear="all"/&gt; </description> 
<pubDate>Mon, 09 Apr 2012 13:50:00 EDT</pubDate>
<link>http://www.nih.gov/researchmatters/april2012/04092012foot.htm</link>
</item>

<item>
<title>Complex Brain Has Simple Grid Structure</title>
<description>&lt;p&gt;&lt;a href=&quot;http://www.nih.gov/researchmatters/april2012/04092012brain.htm&quot;&gt;&lt;img src=&quot;http://www.nih.gov/researchmatters/april2012/images/grid_th.jpg&quot; align=&quot;left&quot; height=&quot;72&quot; width=&quot;72&quot; alt=&quot;Illustration showing 3D grid structure of brain connections." alt="Illustration showing 3D grid structure of brain connections.=&quot;0&quot; /&gt;&lt;/a&gt;New research revealed a wiring diagram of the brain that looks like a simple checkerboard grid. The technique may give insight into the development of disorders like epilepsy, autism and schizophrenia.&lt;/p&gt;&lt;br clear="all"/&gt; </description> 
<pubDate>Mon, 09 Apr 2012 13:50:00 EDT</pubDate>
<link>http://www.nih.gov/researchmatters/april2012/04092012brain.htm</link>
</item>

<item>
<title>Understanding Insulin Sensitivity and Diabetes</title>
<description>&lt;p&gt;&lt;a href=&quot;http://www.nih.gov/researchmatters/april2012/04092012insulin.htm&quot;&gt;&lt;img src=&quot;http://www.nih.gov/researchmatters/april2012/images/diabetes09_th.jpg&quot; align=&quot;left&quot; height=&quot;72&quot; width=&quot;72&quot; alt=&quot;Photo of a woman looking at her reflection in a bathroom mirror and pinching her stomach fat." alt="Photo of a woman looking at her reflection in a bathroom mirror and pinching her stomach fat.=&quot;0&quot; /&gt;&lt;/a&gt;A new discovery helps explain how adipose tissue (fat) affects insulin sensitivity and results in type 2 diabetes. The finding may lead to new strategies for treating the disease.&lt;/p&gt;&lt;br clear="all"/&gt; </description> 
<pubDate>Mon, 09 Apr 2012 13:50:00 EDT</pubDate>
<link>http://www.nih.gov/researchmatters/april2012/04092012insulin.htm</link>
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