NIH Research Matters
February 2013 Archive
February 25, 2013
Predicting Treatment Response to a Rapid Antidepressant
Certain brain activity may predict how well patients with major depressive disorder respond to an experimental antidepressant. The finding suggests that brain imaging might help identify good candidates for the treatment.
Boosting Cell Defenses
Scientists designed a compound that induces a cell “housekeeping” process that may help fight cancer, infection, neurodegenerative disease and aging. The compound successfully protected laboratory mice from deadly infections.
High Salt Detected by Sour and Bitter Taste Cells
Researchers discovered that high levels of salt trigger both sour- and bitter-sensing taste cells in mice. The finding may help explain why we find high levels of salt unappetizing.
February 11, 2013
Many Doctors Don't Ask Teens About Alcohol
In a new study, more than one-third of 10th graders reported recent alcohol use. But many didn't recall their doctors asking them about it. The finding reveals important missed opportunities to prevent underage alcohol use.
Sleep and Memory in the Aging Brain
New research reveals a connection between sleep and memory and sheds light on why forgetfulness is common in the elderly. The study also suggests that boosting sleep quality may help improve memory.
Sensing Positive Touch
Scientists have identified a rare type of neuron in mice that's responsible for detecting the pleasant stroking of skin. The finding opens the door to exploring the molecules and neural pathways that recognize a positive touch.
February 4, 2013
H1N1 Flu Shots Safe for Pregnant Women
A study of pregnant women in Norway found that those infected with the 2009 H1N1 influenza virus had an increased risk of miscarriages and stillbirths. But those vaccinated against the virus had no increased risk of pregnancy loss.
Dengue Vaccine Shows Early Promise
Just one dose of a low-cost vaccine proved safe and stimulated a strong immune response against the dengue virus in most participants in an early-stage clinical trial. With further development, the vaccine may help ease the burden of dengue fever in developing countries.
Strategy May Improve Survival after Shock
Scientists found that blocking digestive enzymes in rat intestines increases survival, reduces organ damage and improves recovery after shock. The innovative approach may lead to therapies to improve patient outcome following shock, sepsis and multiorgan failure.
Editor’s Picks
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About NIH Research Matters
Harrison Wein, Ph.D., Editor
Vicki Contie, Assistant Editor
NIH Research Matters is a weekly update of NIH research highlights from the Office of Communications and Public Liaison, Office of the Director, National Institutes of Health.










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