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NIH Research Matters

April 2011 Archive

April 25, 2011

Photo of a doctor looking at an x-ray.

Cancer Burden Shifts for HIV-Infected Population

The distribution of cancers among people living with HIV and AIDS in the United States has undergone a dramatic shift. Certain cancers long associated with AIDS progression have declined, while other cancers are on the rise.

Photo of broccoli

Broccoli Compound May Combat COPD

In chronic obstructive pulmonary disease, damage to immune cells limits the lungs' ability to fight off bacterial infections. According to a new study, boosting the activity of a molecule in these cells can restore their defenses.

Photo of an older man flexing large biceps.

Gene Could Hold Key to Muscle Repair

Researchers have identified a gene that is critical for maintaining and regenerating muscle. The finding may lead to therapies for muscle-wasting diseases and age-related muscle decline.

April 18, 2011

Photo of a woman wearing a wide-brimmed hat.

A Genomic Survey of Melanoma

Researchers have performed the first comprehensive genomic analysis of melanoma, the deadliest form of skin cancer. The findings provide a better basis for understanding melanoma and developing new treatment strategies.

Digitally enhanced photograph of a human heart.

Blood DNA Test Detects Heart Transplant Rejection

A new type of test that detects "foreign" DNA in a patientís bloodstream may provide early clues to organ rejection. The technique could offer an alternative to the expensive and invasive biopsies now used to detect transplant failure.

Illustration of a circular molecular structure.

Surprising Molecule Tied to Rare Disease

Researchers have found that defects in a molecule called a small nuclear RNA (snRNA) are responsible for a rare genetic disease. The finding represents the first time that snRNAs have been linked to disease.

April 11, 2011

Photo of two older men playing chess.

New Genetic Risk Factors for Alzheimer's Disease

In 2 massive studies, scientists from around the world identified 5 new genes that may be risk factors for late-onset Alzheimerís disease.

Microscope image shows bright green splotches near thick orange lines.

More Young Neurons Equals Better Brain Function

Boosting the survival of neurons in the brainís memory hub improved the cognitive ability of mice. Adding exercise produced antidepressant effects. The findings suggest new strategies for treating cognitive, mood and anxiety disorders.

Microscope image of green chromosomes dotted with red spots.

Mapping Recombination Hotspots

Researchers zoomed in on mouse chromosomes to map hotspots of genetic recombination—sites where DNA breaks and reforms to shuffle genes. The findings will help give insight into how mammals evolve and respond to their environments.

April 4, 2011

Microscope image of several small round cells on a larger, spiky cell.

Breaking Down Pancreatic Tumor Defenses

A new approach for attacking pancreatic tumors may lead to improved therapy for patients with inoperable disease, scientists report. The strategy offers hope for more effective techniques to eliminate tumors.

Photo of an eye.

Eye Development Error Causes Cataracts, Glaucoma

Researchers have found a common mutation in patients with pediatric cataracts that could broaden our understanding of how the eye develops.

Microscope image of red circular areas in 2 cells.

Genetic Variations Affect Control of the Genome

Genetic variations that lie outside of any known genes can lead to disease. Findings from a new study may help explain why.

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About NIH Research Matters

Editor: Harrison Wein, Ph.D.
Assistant Editors: Vicki Contie, Carol Torgan, Ph.D.

NIH Research Matters is a weekly update of NIH research highlights from the Office of Communications and Public Liaison, Office of the Director, National Institutes of Health.

ISSN 2375-9593

This page last reviewed on December 3, 2012

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