NIH Research Matters
April 20, 2015
An experimental antibody significantly reduced HIV levels in infected people for as long as 28 days. The approach might help to combat a wide range of HIV strains.
A common over-the-counter allergy drug lowered hepatitis C virus levels in infected mice. The drug is currently being tested in patients with chronic hepatitis C.
A structural study revealed how an antibiotic called borrelidin stops bacterial growth. The findings may help researchers design improved drugs to fight infections.
April 13, 2015
An experimental Ebola vaccine called VSV-ZEBOV was safe and produced robust antibody responses in all the healthy adults who received it. Itís now being tested in Liberia.
Using an advanced genetic test, researchers detected diffuse large B-cell lymphoma in blood before it could be seen on CT scans. The technique could improve disease monitoring.
Researchers identified beige fat cells, which burn energy rather than store it, in humans. The finding may lead to new ways to engineer fat cells to fight obesity.
March 30, 2015
Researchers used a tetanus booster to enhance the effects of an experimental immunotherapy against glioblastoma, a deadly type of brain cancer.
Pathologists asked to interpret a difficult set of breast biopsy slides accurately made most diagnoses, but the results suggest strategies for future improvement.
Mice with immune cells unable to use vitamin D developed precursors of heart disease and type 2 diabetes. The mechanisms uncovered may lead to novel therapies.
March 23, 2015
Researchers found that a set of genetic variants could identify people at risk for coronary heart disease and who would benefit most from statin therapy.
Physical activity may help improve movement problems linked to brain lesions in older people. The results highlight the importance of an active lifestyle for older adults.
Scientists used a powerful new technique to systematically turn off all the genes in mouse lung cancer cells and test how they affect tumor growth and metastasis.
March 16, 2015
Falling air pollution levels in Southern California were associated with improvements in childrenís lung function during a critical period of growth and development.
A study in mice suggests that common food additives called emulsifiers might play a role in the increasing incidence of obesity and chronic inflammatory bowel disease.
Genetic switches called super-enhancers help regulate the human immune system. The finding will inform research into autoimmune disorders such as rheumatoid arthritis.
March 9, 2015
Infants who regularly consumed peanut products from infancy to age 5 proved less likely to become allergic to peanuts.
More than 100 reference human epigenomes from a broad range of cell and tissue types revealed epigenomic factors associated with age, sex, tissue type, and various diseases.
Scientists created a compound that could potentially lead to a long-lasting method of HIV prevention and treatment.
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About NIH Research Matters
Editor: Harrison Wein, Ph.D.
Assistant Editors: Vicki Contie, Carol Torgan, Ph.D.
NIH Research Matters is a weekly update of NIH research highlights from the Office of Communications and Public Liaison, Office of the Director, National Institutes of Health.