NIH Research Matters
October 20, 2014
Certain heart-related risk factors are present early in people diagnosed with schizophrenia spectrum disorders. The findings highlight early treatment opportunities.
An experimental vaccine against H7N9 avian influenza prompted substantial immune responses in 59% of volunteers. The approach could lead to improved flu vaccines.
Researchers transformed human stem cells into pancreatic beta cells that produce insulin and respond to glucose. The finding could lead to new therapies to treat diabetes.
October 6, 2014
Pregnant women given computer-based information about prenatal screening were more likely to skip testing, especially invasive tests—even when the tests were free.
A study in mice revealed how diet-induced changes to intestinal bacteria can influence autoinflammatory disease. The results could guide new approaches to these diseases.
In a proof-of-principle study, scientists identified a compound that can correct a cellular defect that causes a rare kidney disease.
September 29, 2014
A zebrafish study shed light on how the structure of the face forms. Problems with equivalent genes in people can cause facial defects and other developmental issues.
Researchers developed microgel particles that mimic platelets and help form blood clots. The approach could lead to new treatments for uncontrolled bleeding.
Scientists designed a way to target and destroy specific DNA sequences in microbes. The approach might one day be used against pathogenic bacteria resistant to multiple antibiotics.
September 22, 2014
Activating certain molecules in key tissues slowed aging in fruit flies. The findings could lead to a better understanding of aging processes in people.
By manipulating a protein called Stat3, researchers regenerated muscle in mice. The approach may point the way to treatments for muscle-wasting diseases.
Researchers described how a cellís nucleus can act as a piston to propel it through a 3-D matrix. The findings may help in the design of strategies to regenerate tissue and inhibit metastatic cells.
September 15, 2014
Scientists used genomic sequencing technologies to identify the origin and track transmission of the Ebola virus in the current outbreak in Africa.
By analyzing the genomes of humans, flies, and worms, scientists are gaining insights into complex biological processes that are vital to human biology and disease.
Researchers identified a molecule that plays a role in heart failure in mice. The findings may lead to a new therapeutic agent to treat this common condition.
August 25, 2014
A combination drug treatment substantially reduced malaria in young children in Africa. The treatment could help reduce the disease burden among those most at risk.
A chikungunya vaccine gave encouraging results in an early-stage clinical trial. A vaccine could prevent outbreaks of the disease, which recently reached the U.S. mainland.
Scientists determined the detailed structural states of the glutamate receptor, which is involved in learning, memory, and several diseases.
NIH Research Matters
Bldg. 31, Rm. 5B64A, MSC 2094
Bethesda, MD 20892-2094
About NIH Research Matters
Editor: Harrison Wein, Ph.D.
Assistant Editors: Vicki Contie, Carol Torgan, Ph.D.
NIH Research Matters is a weekly update of NIH research highlights from the Office of Communications and Public Liaison, Office of the Director, National Institutes of Health.