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NIH Research Matters

May 4, 2015

Ebola Virus.

Lipid Nanoparticle Therapeutic Treats Ebola in Monkeys

A newly designed agent was effective in treating monkeys infected with a deadly Ebola virus strain. The therapy is now being tested in Sierra Leone in people infected with Ebola.

Illustration of cylindrical device inside a tumor.

Devices Assess Cancer Drugs in Tumors

Two devices, developed independently, can gauge how tumors respond to various drugs. With further development, they could help determine ideal individual treatments.

Female doctor measuring blood pressure of senior woman

Structure of a Key Blood Pressure Regulator

Scientists revealed the molecular structure of a key target for blood pressure medications. The findings may aid the development of blood pressure drugs with fewer side effects.

April 27, 2015

Bag of transfusion blood.

Storing Blood Before Transfusion

Among patients undergoing complex cardiac surgeries, a clinical study found no advantage to only transfusing red blood cells stored for shorter periods of time.

Brain image.

Brain Mapping of Language Impairments

Researchers mapped different language impairments to specific brain regions to reveal the basic organization of our language system.

Artistís representation of oligodendrocyte.

Drugs Lessen Multiple Sclerosis Damage in Mice

In a mouse study, 2 drugs already on the market activated stem cells and repaired the type of brain damage seen in multiple sclerosis. The finding might lead to novel therapies.

April 20, 2015

HIV-infected immune cells.

HIV Immunotherapy Promising in First Human Study

An experimental antibody significantly reduced HIV levels in infected people for as long as 28 days. The approach might help to combat a wide range of HIV strains.

3d rendered illustration of hepatitis virus.

Allergy Drug Treats Hepatitis C in Mice

A common over-the-counter allergy drug lowered hepatitis C virus levels in infected mice. The drug is currently being tested in patients with chronic hepatitis C.

Schematic map showing the 4 sites occupied by borrelidin.

Scientists Discover Antibiotic Mechanism

A structural study revealed how an antibiotic called borrelidin stops bacterial growth. The findings may help researchers design improved drugs to fight infections.

April 13, 2015

Ebola virus.

Ebola Vaccine Candidate Promising in Early Study

An experimental Ebola vaccine called VSV-ZEBOV was safe and produced robust antibody responses in all the healthy adults who received it. Itís now being tested in Liberia.

Illustration of the lymphatic system.

Tumor DNA in Blood Reveals Lymphoma Progression

Using an advanced genetic test, researchers detected diffuse large B-cell lymphoma in blood before it could be seen on CT scans. The technique could improve disease monitoring.

Beige fat cells.

Insights into Energy-Burning Fat Cells

Researchers identified beige fat cells, which burn energy rather than store it, in humans. The finding may lead to new ways to engineer fat cells to fight obesity.

March 30, 2015

Dendritic cell.

Boosting Immunotherapy Against Brain Cancer

Researchers used a tetanus booster to enhance the effects of an experimental immunotherapy against glioblastoma, a deadly type of brain cancer.

Woman consulting with her doctor.

Interpreting Breast Biopsies

Pathologists asked to interpret a difficult set of breast biopsy slides accurately made most diagnoses, but the results suggest strategies for future improvement.

Illustration of white blood cells.

How Vitamin D May Affect Heart Disease, Diabetes

Mice with immune cells unable to use vitamin D developed precursors of heart disease and type 2 diabetes. The mechanisms uncovered may lead to novel therapies.

March 23, 2015

Illustration of DNA, blood cells, and a blood vessel.

Genetics Help Predict Heart Disease Risk, Statin Benefits

Researchers found that a set of genetic variants could identify people at risk for coronary heart disease and who would benefit most from statin therapy.

Healthy older cyclists.

Physical Activity May Reduce Age-Related Movement Problems

Physical activity may help improve movement problems linked to brain lesions in older people. The results highlight the importance of an active lifestyle for older adults.

Illustration of cells in a tumor.

Novel Approach Gives Insights Into Tumor Development

Scientists used a powerful new technique to systematically turn off all the genes in mouse lung cancer cells and test how they affect tumor growth and metastasis.

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About NIH Research Matters

Editor: Harrison Wein, Ph.D.
Assistant Editors: Vicki Contie, Carol Torgan, Ph.D.

NIH Research Matters is a weekly update of NIH research highlights from the Office of Communications and Public Liaison, Office of the Director, National Institutes of Health.

ISSN 2375-9593

Research News from NIH and Grantees

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This page last reviewed on May 4, 2015

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